Structural basis for recognition of cellular and viral ligands by NK cell receptors

Natural killer (NK) cells are key components of innate immune responses to tumors and viral infections. NK cell function is regulated by NK cell receptors that recognize both cellular and viral ligands, including MHC, MHC-like, and non-MHC molecules. These receptors include Ly49s, KIRs, LILRs, and N...

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Bibliographic Details
Main Authors: Roy eMariuzza, Yili eLi
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-03-01
Series:Frontiers in Immunology
Subjects:
KIR
MHC
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00123/full