Intranasal Vaccine Using P10 Peptide Complexed within Chitosan Polymeric Nanoparticles as Experimental Therapy for Paracoccidioidomycosis in Murine Model

Intranasal Vaccine Using P10 Peptide Complexed within Chitosan Polymeric Nanoparticles as Experimental Therapy for Paracoccidioidomycosis in Murine Model

Paracoccidioidomycosis (PCM) is a granulomatous fungal disease caused by the dimorphic fungal species of <i>Paracoccidioides</i>, which mainly affects the lungs. Modern strategies for the treatment and/or prevention of PCM are based on a Th1-type immune response, which is important for c...

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Bibliographic Details
Main Authors: Samuel Rodrigues Dos Santos Junior, Francenya Kelley Lopes da Silva, Lucas Santos Dias, Ana Camila Oliveira Souza, Marcelo Valdemir de Araujo, Leandro Buffoni Roque da Silva, Luiz R. Travassos, Andre Correa Amaral, Carlos P. Taborda
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Journal of Fungi
Subjects:
paracoccidioidomycosis
P10 peptide
nanovaccine
polymeric nanoparticles
antifungal therapy
Online Access:https://www.mdpi.com/2309-608X/6/3/160

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https://www.mdpi.com/2309-608X/6/3/160

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