Tspan8 and Tspan8/CD151 knockout mice unravel the contribution of tumor and host exosomes to tumor progression

Tspan8 and Tspan8/CD151 knockout mice unravel the contribution of tumor and host exosomes to tumor progression

Abstract Background The tetraspanins Tspan8 and CD151 promote metastasis, exosomes (Exo) being suggested to be important in the crosstalk between tumor and host. The contribution of Tspan8 and CD151 to host versus tumor-derived exosome (TEX) activities being not defined, we approached the questions...

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Bibliographic Details
Main Authors: Kun Zhao, Zhe Wang, Thilo Hackert, Claudia Pitzer, Margot Zöller
Format: Article
Language:English
Published: BMC 2018-12-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Tspan8 knockout
CD151 knockout
Exosomes
Metastasis
Angiogenesis
Hematopoiesis
Online Access:http://link.springer.com/article/10.1186/s13046-018-0961-6

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http://link.springer.com/article/10.1186/s13046-018-0961-6

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