Early increase in blood supply (EIBS) is associated with tumor risk in the Azoxymethane model of colon cancer

Early increase in blood supply (EIBS) is associated with tumor risk in the Azoxymethane model of colon cancer

Abstract Background The present study aimed to investigate the role of blood supply in early tumorigenesis in colorectal cancer. We leveraged the renin angiotensin system (RAS) to alter colonic blood supply and determine the effect on tumor initiation and progression. Methods To test the effect of b...

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Bibliographic Details
Main Authors: Sarah Ruderman, Adam Eshein, Vesta Valuckaite, Urszula Dougherty, Anas Almoghrabi, Andrew Gomes, Ajaypal Singh, Baldeep Pabla, Hemant K. Roy, John Hart, Marc Bissonnette, Vani Konda, Vadim Backman
Format: Article
Language:English
Published: BMC 2018-08-01
Series:BMC Cancer
Subjects:
Colorectal cancer
Early increase in blood supply
Angiogenesis
Renin angiotensin system
Field effect of carcinogenesis
Online Access:http://link.springer.com/article/10.1186/s12885-018-4709-7

Internet

http://link.springer.com/article/10.1186/s12885-018-4709-7

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