Ganglioside GM1 Targets Astrocytes to Stimulate Cerebral Energy Metabolism

Gangliosides are major constituents of the plasma membrane and are known to promote a number of physiological actions in the brain, including synaptic plasticity and neuroprotection. In particular, the ganglioside GM1 was found to have a wide range of preclinical and clinical benefits in brain disea...

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Bibliographic Details
Main Authors: Charles Finsterwald, Sara Dias, Pierre J. Magistretti, Sylvain Lengacher
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Pharmacology
Subjects:
GM1
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.653842/full