A protein complex containing the conserved Swi2/Snf2-related ATPase Swr1p deposits histone variant H2A.Z into euchromatin.

The conserved histone variant H2A.Z functions in euchromatin to antagonize the spread of heterochromatin. The mechanism by which histone H2A is replaced by H2A.Z in the nucleosome is unknown. We identified a complex containing 13 different polypeptides associated with a soluble pool of H2A.Z in Sacc...

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Bibliographic Details
Main Authors: Michael S Kobor, Shivkumar Venkatasubrahmanyam, Marc D Meneghini, Jennifer W Gin, Jennifer L Jennings, Andrew J Link, Hiten D Madhani, Jasper Rine
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2004-05-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.0020131