Data-driven, voxel-based analysis of brain PET images: Application of PCA and LASSO methods to visualize and quantify patterns of neurodegeneration.

Data-driven, voxel-based analysis of brain PET images: Application of PCA and LASSO methods to visualize and quantify patterns of neurodegeneration.

Spatial patterns of radiotracer binding in positron emission tomography (PET) images may convey information related to the disease topology. However, this information is not captured by the standard PET image analysis that quantifies the mean radiotracer uptake within a region of interest (ROI). On...

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Bibliographic Details
Main Authors: Ivan S Klyuzhin, Jessie F Fu, Andy Hong, Matthew Sacheli, Nikolay Shenkov, Michele Matarazzo, Arman Rahmim, A Jon Stoessl, Vesna Sossi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6218048?pdf=render

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http://europepmc.org/articles/PMC6218048?pdf=render

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