The m6A Reader YTHDF1 Facilitates the Tumorigenesis and Metastasis of Gastric Cancer via USP14 Translation in an m6A-Dependent Manner

The m6A Reader YTHDF1 Facilitates the Tumorigenesis and Metastasis of Gastric Cancer via USP14 Translation in an m6A-Dependent Manner

ObjectivesN6-methyladenosine (m6A) RNA methylation is implicated in the progression of multiple cancers via influencing mRNA modification. YTHDF1 can act as an oncogene in gastric cancer (GC), while the biological mechanisms via which YTHDF1 regulates gastric tumorigenesis through m6A modification r...

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Bibliographic Details
Main Authors: Xiao-Yu Chen, Rui Liang, You-Cai Yi, Hui-Ning Fan, Ming Chen, Jing Zhang, Jin-Shui Zhu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
tumorigenesis
N6-methyladenosine
metastasis
gastric cancer
YTHDF1
USP14
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.647702/full

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https://www.frontiersin.org/articles/10.3389/fcell.2021.647702/full

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