Prenatal Exposure to a Maternal High-Fat Diet Affects Histone Modification of Cardiometabolic Genes in Newborn Rats

Prenatal Exposure to a Maternal High-Fat Diet Affects Histone Modification of Cardiometabolic Genes in Newborn Rats

Infants born to women with diabetes or obesity are exposed to excess circulating fuels during fetal heart development and are at higher risk of cardiac diseases. We have previously shown that late-gestation diabetes, especially in conjunction with a maternal high-fat (HF) diet, impairs cardiac funct...

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Bibliographic Details
Main Authors: Bijaya Upadhyaya, Tricia Larsen, Shivon Barwari, Eli J. Louwagie, Michelle L. Baack, Moul Dey
Format: Article
Language:English
Published: MDPI AG 2017-04-01
Series:Nutrients
Subjects:
cardiometabolic disease
chromatin-immunoprecipitation sequencing
developmental programing
histone modifications
maternal high-fat diet
Online Access:http://www.mdpi.com/2072-6643/9/4/407

Internet

http://www.mdpi.com/2072-6643/9/4/407

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