Dasatinib reverses drug resistance by downregulating MDR1 and Survivin in Burkitt lymphoma cells

Dasatinib reverses drug resistance by downregulating MDR1 and Survivin in Burkitt lymphoma cells

Abstract Background Current chemotherapies for Burkitt lymphoma (BL) have dramatically improved its clinical outcome. However, chemoresistance can lead to chemotherapy failure and very poor prognosis; thus, novel strategies are urgently required for patients with drug-resistant BL. To investigate th...

Full description

Bibliographic Details
Main Authors: Mitsuki Tabata, Masanobu Tsubaki, Tomoya Takeda, Keisuke Tateishi, Katsumasa Tsurushima, Motohiro Imano, Takao Satou, Toshihiko Ishizaka, Shozo Nishida
Format: Article
Language:English
Published: BMC 2020-03-01
Series:BMC Complementary Medicine and Therapies
Subjects:
Drug resistance
MDR1
Survivin
Src
Dasatinib
Online Access:http://link.springer.com/article/10.1186/s12906-020-2879-8

Internet

http://link.springer.com/article/10.1186/s12906-020-2879-8

Similar Items