CTCF genomic binding sites in Drosophila and the organisation of the bithorax complex.

Insulator or enhancer-blocking elements are proposed to play an important role in the regulation of transcription by preventing inappropriate enhancer/promoter interaction. The zinc-finger protein CTCF is well studied in vertebrates as an enhancer blocking factor, but Drosophila CTCF has only been c...

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Bibliographic Details
Main Authors: Eimear E Holohan, Camilla Kwong, Boris Adryan, Marek Bartkuhn, Martin Herold, Rainer Renkawitz, Steven Russell, Robert White
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-07-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC1904468?pdf=render