CTCF genomic binding sites in Drosophila and the organisation of the bithorax complex.
Insulator or enhancer-blocking elements are proposed to play an important role in the regulation of transcription by preventing inappropriate enhancer/promoter interaction. The zinc-finger protein CTCF is well studied in vertebrates as an enhancer blocking factor, but Drosophila CTCF has only been c...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2007-07-01
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Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC1904468?pdf=render |