Computational insight into crucial binding features for metabolic specificity of cytochrome P450 17A1
In present study we aimed to explore the possible structural feature of Cytochrome P450 (CYP) 17A1 that contributes to the metabolic specificity. The predicable 3D-QSAR (Quantitative Structure-Activity Relationships) models were first developed with CoMFA (Comparative Molecular Field Analysis) and C...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2019-01-01
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| Series: | Informatics in Medicine Unlocked |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2352914819300188 |