Association between the PARP1 Val762Ala polymorphism and cancer risk: evidence from 43 studies.

Poly (ADP-ribose) polymerase-1 (PARP-1) plays critical roles in the detection and repair of damaged DNA, as well as cell proliferation and death. Numerous studies have examined the associations between PARP1 Val762Ala (rs1136410 T>C) polymorphism and cancer susceptibility; nevertheless, the findi...

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Bibliographic Details
Main Authors: Rui-Xi Hua, He-Ping Li, Yan-Bing Liang, Jin-Hong Zhu, Bing Zhang, Sheng Ye, Qiang-Sheng Dai, Shi-Qiu Xiong, Yong Gu, Xiang-Zhou Sun
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3904982?pdf=render