Acetamidine-Based iNOS Inhibitors as Molecular Tools to Counteract Inflammation in BV2 Microglial Cells
Neurodegenerative diseases are associated with increased levels of nitric oxide (NO) mainly produced by microglial cells through inducible nitric oxide synthase (iNOS) whose expression is induced by inflammatory stimuli. NO can both exert cytotoxic functions and induce a metabolic switch by inhibiti...
Main Authors: | Silvia Grottelli, Rosa Amoroso, Lara Macchioni, Fiorella D’Onofrio, Katia Fettucciari, Ilaria Bellezza, Cristina Maccallini |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-06-01
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Series: | Molecules |
Subjects: | |
Online Access: | https://www.mdpi.com/1420-3049/25/11/2646 |
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