1-Hydroxy-8-methoxy-anthraquinon reverses cisplatin resistance by inhibiting 6PGD in cancer cells

Targeting 6-phosphogluconate dehydrogenase (6PGD) can inhibit cancer cell proliferation and tumor growth. However, the relationship between 6PGD and cisplatin resistance still needs further study. Cisplatin-sensitive and cisplatin-resistant ovarian cancer OV2008 and C13* lines and lung cancer A549 a...

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Bibliographic Details
Main Authors: Zhang Huamin, Zhang Haowei, Wang Sihui, Ni Zhihai, Wang Tiejun
Format: Article
Language:English
Published: De Gruyter 2019-11-01
Series:Open Life Sciences
Subjects:
s3
Online Access:https://doi.org/10.1515/biol-2019-0051