Endoglin potentiates nitric oxide synthesis to enhance definitive hematopoiesis

Endoglin potentiates nitric oxide synthesis to enhance definitive hematopoiesis

During embryonic development, hematopoietic cells develop by a process of endothelial-to hematopoietic transition of a specialized population of endothelial cells. These hemogenic endothelium (HE) cells in turn develop from a primitive population of FLK1+ mesodermal cells. Endoglin (ENG) is an acces...

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Bibliographic Details
Main Authors: Rabab Nasrallah, Kathy Knezevic, Thuan Thai, Shane R. Thomas, Berthold Göttgens, Georges Lacaud, Valerie Kouskoff, John E. Pimanda
Format: Article
Language:English
Published: The Company of Biologists 2015-07-01
Series:Biology Open
Subjects:
Endoglin
Nitric oxide
FLK1
SMAD2
Hemogenic endothelium
Hematopoiesis
Online Access:http://bio.biologists.org/content/4/7/819

Internet

http://bio.biologists.org/content/4/7/819

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