Functional Heterogeneity of Protein Kinase A Activation in Multipotent Stromal Cells

Functional Heterogeneity of Protein Kinase A Activation in Multipotent Stromal Cells

Multipotent stromal cells (MSC) demonstrate remarkable functional heterogeneity; however, its molecular mechanisms remain largely obscure. In this study, we explored MSC response to hormones, which activate Gs-protein / cyclic AMP (cAMP) / protein kinase A (PKA) dependent signaling, at the single ce...

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Bibliographic Details
Main Authors: Pyotr A. Tyurin-Kuzmin, Maxim N. Karagyaur, Konstantin Yu. Kulebyakin, Daniyar T. Dyikanov, Vadim I. Chechekhin, Anastasiya M. Ivanova, Mariya N. Skryabina, Mikhail S. Arbatskiy, Veronika Yu. Sysoeva, Natalia I. Kalinina, Vsevolod A. Tkachuk
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:International Journal of Molecular Sciences
Subjects:
multipotent stromal cells
mesenchymal stem/stromal cells
protein kinase A
functional heterogeneity
single cell analysis
intracellular signaling
Online Access:https://www.mdpi.com/1422-0067/21/12/4442

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https://www.mdpi.com/1422-0067/21/12/4442

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