In vivo hepatotoxicity screening of different extracts, components, and constituents of Polygoni Multiflori Thunb. in zebrafish (Danio rerio) larvae

In vivo hepatotoxicity screening of different extracts, components, and constituents of Polygoni Multiflori Thunb. in zebrafish (Danio rerio) larvae

Polygonum multiflorum Thunb. (PM) is a traditional Chinese medicine, commonly used to treat a variety of diseases. However, the hepatotoxicity associated with PM hampers its clinical application and development. In this study, we refined the zebrafish hepatotoxicity model with regard to the followin...

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Bibliographic Details
Main Authors: Hong-Ying Li, Jian-Bo Yang, Wan-Fang Li, Cai-Xia Qiu, Guang Hu, Shu-Ting Wang, Yun-Fei Song, Hui-Yu Gao, Yue Liu, Qi Wang, Ying Wang, Xian-Long Cheng, Feng Wei, Hong-Tao Jin, Shuang-Cheng Ma
Format: Article
Language:English
Published: Elsevier 2020-11-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Zebrafish hepatotoxicity model
Dianthrone
Emodin
Emodin-8-O-β-D-glucopyranoside
Chrysophanol
[Trans]-emodin-emodin dianthrone
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332220307174

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http://www.sciencedirect.com/science/article/pii/S0753332220307174

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