DC Subsets Regulate Humoral Immune Responses by Supporting the Differentiation of Distinct Tfh Cells

DC Subsets Regulate Humoral Immune Responses by Supporting the Differentiation of Distinct Tfh Cells

To determine the contribution of skin DC subsets in the regulation of humoral immunity, we used a well-characterized antigen targeting system to limit antigen availability and presentation to certain skin-derived DC subsets. Here we show that delivery of foreign antigen to steady state Langerhans ce...

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Bibliographic Details
Main Authors: Aurélie Bouteau, Jérôme Kervevan, Qingtai Su, Sandra M. Zurawski, Vanessa Contreras, Nathalie Dereuddre-Bosquet, Roger Le Grand, Gerard Zurawski, Sylvain Cardinaud, Yves Levy, Botond Z. Igyártó
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Immunology
Subjects:
dendritic cells
humoral immune response
Tfh cell
B cell
regulation
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01134/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.01134/full

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