NOD2 Expression in Intestinal Epithelial Cells Protects Toward the Development of Inflammation and Associated CarcinogenesisSummary

Nucleotide-binding oligomerization domain 2 (NOD2) is an intracellular pattern recognition receptor that senses bacterial peptidoglycan-conserved motifs in cytosol and stimulates host immune response including epithelial and immune cells. The association of NOD2 mutations with a number of inflammato...

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Bibliographic Details
Main Authors: Audrey Ferrand, Ziad Al Nabhani, Núria Solà Tapias, Emmanuel Mas, Jean-Pierre Hugot, Frédérick Barreau
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X18301553