MAPK, AKT/FoxO3a and mTOR pathways are involved in cadmium regulating the cell cycle, proliferation and apoptosis of chicken follicular granulosa cells

MAPK, AKT/FoxO3a and mTOR pathways are involved in cadmium regulating the cell cycle, proliferation and apoptosis of chicken follicular granulosa cells

The occurrence of cadmium (Cd) in feed is a major problem in animal health and production. Studies have confirmed that Cd depresses egg production of laying hens, which is closely related to follicular atresia. This study aimed to assess the toxic impacts of Cd on the ovarian tissue, and to examine...

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Bibliographic Details
Main Authors: Mingkun Zhu, Sasa Miao, Wenting Zhou, Shaaban Saad Elnesr, Xinyang Dong, Xiaoting Zou
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Cadmium
AKT/FoxO3a
MAPKs
MTOR
Cell proliferation
Cell apoptosis
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651321002025

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http://www.sciencedirect.com/science/article/pii/S0147651321002025

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