Unbiased functional clustering of gene variants with a phenotypic-linkage network.

Groupwise functional analysis of gene variants is becoming standard in next-generation sequencing studies. As the function of many genes is unknown and their classification to pathways is scant, functional associations between genes are often inferred from large-scale omics data. Such data types--in...

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Bibliographic Details
Main Authors: Frantisek Honti, Stephen Meader, Caleb Webber
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-08-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC4148192?pdf=render