Front-Line Window Therapy with Temozolomide and Irinotecan in Patients with Primary Disseminated Multifocal Ewing Sarcoma: Results of the ISG/AIEOP EW-2 Study

Front-Line Window Therapy with Temozolomide and Irinotecan in Patients with Primary Disseminated Multifocal Ewing Sarcoma: Results of the ISG/AIEOP EW-2 Study

Purpose: The main objective was to evaluate the activity and tolerability of TEMIRI as a front-line treatment in primary disseminated Ewing sarcoma (PDMES) using the RECIST 1.1 criteria. The secondary objectives included the assessment of toxicity and the performance status/symptom changes. Methods:...

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Bibliographic Details
Main Authors: Sebastian Dorin Asaftei, Nadia Puma, Anna Paioli, Marco Petraz, Carlo Morosi, Marta Podda, Angela Tamburini, Emanuela Palmerini, Luca Coccoli, Giovanni Grignani, Carla Manzitti, Rossella Bertulli, Francesco De Leonardis, Marco Rabusin, Anna Campello, Elisa Tirtei, Piero Picci, Arcangelo Prete, Alessandra Longhi, Franca Fagioli, Roberto Luksch
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Cancers
Subjects:
primary disseminated multifocal Ewing sarcoma
temozolomide
irinotecan
front-line treatment
Online Access:https://www.mdpi.com/2072-6694/13/12/3046

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https://www.mdpi.com/2072-6694/13/12/3046

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