The genetic landscape of ganglioglioma

The genetic landscape of ganglioglioma

Abstract Ganglioglioma is the most common epilepsy-associated neoplasm that accounts for approximately 2% of all primary brain tumors. While a subset of gangliogliomas are known to harbor the activating p.V600E mutation in the BRAF oncogene, the genetic alterations responsible for the remainder are...

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Bibliographic Details
Main Authors: Melike Pekmezci, Javier E. Villanueva-Meyer, Benjamin Goode, Jessica Van Ziffle, Courtney Onodera, James P. Grenert, Boris C. Bastian, Gabriel Chamyan, Ossama M. Maher, Ziad Khatib, Bette K. Kleinschmidt-DeMasters, David Samuel, Sabine Mueller, Anuradha Banerjee, Jennifer L. Clarke, Tabitha Cooney, Joseph Torkildson, Nalin Gupta, Philip Theodosopoulos, Edward F. Chang, Mitchel Berger, Andrew W. Bollen, Arie Perry, Tarik Tihan, David A. Solomon
Format: Article
Language:English
Published: BMC 2018-06-01
Series:Acta Neuropathologica Communications
Subjects:
Ganglioglioma
Epilepsy
Seizures
Glioneuronal tumor
Targeted next-generation sequencing
Ras-Raf-MEK-ERK
Online Access:http://link.springer.com/article/10.1186/s40478-018-0551-z

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http://link.springer.com/article/10.1186/s40478-018-0551-z

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