Ventral hippocampal projections to the medial prefrontal cortex regulate social memory
Inputs from the ventral hippocampus (vHIP) to the medial prefrontal cortex (mPFC) are implicated in several neuropsychiatric disorders. Here, we show that the vHIP-mPFC projection is hyperactive in the Mecp2 knockout mouse model of the autism spectrum disorder Rett syndrome, which has deficits in so...
Main Authors: | Mary L Phillips, Holly Anne Robinson, Lucas Pozzo-Miller |
---|---|
Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2019-05-01
|
Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/44182 |
Similar Items
-
Interaction of basolateral amygdala, ventral hippocampus and medial prefrontal cortex regulates the consolidation and extinction of social fear
by: Chu-Chu Qi, et al.
Published: (2018-03-01) -
Pre-synaptic and post-synaptic pathways from the hippocampus to medial prefrontal cortex in Rhesus monkeys
by: Onochie, Ifeanyirochukwu
Published: (2018) -
Effects of Melatonin Levels on Neurotoxicity of the Medial Prefrontal Cortex in a Rat Model of Parkinson's Disease
by: Yan Li, et al.
Published: (2017-01-01) -
The Role of Medial Prefrontal Cortex and Ventral Tegmental Areas in Withdrawal Syndrome in Morphine Addicted Male Rats
by: Asal Keramatian, et al.
Published: (2020-12-01) -
Different forms of decision-making involve changes in the synaptic strength of the thalamic, hippocampal, and amygdalar afferents to the medial prefrontal cortex
by: Juan Carlos López-Ramos, et al.
Published: (2015-01-01)