Physico-Chemical and Pharmaco-Technical Characterization of Inclusion Complexes Formed by Rutoside with β-Cyclodextrin and Hydroxypropyl-β-Cyclodextrin Used to Develop Solid Dosage Forms

Physico-Chemical and Pharmaco-Technical Characterization of Inclusion Complexes Formed by Rutoside with β-Cyclodextrin and Hydroxypropyl-β-Cyclodextrin Used to Develop Solid Dosage Forms

The aim of our study was to obtain rutoside (RUT) inclusion complexes in β-cyclodextrin (β-CD) and in hydroxypropyl-β-cyclodextrin (HP-β-CD), in a 1:1 molar ratio, using the lyophilization method of complexation in solution. The complexes were confirmed and characterized, in comparison with the raw...

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Bibliographic Details
Main Authors: Teodora Balaci, Bruno Velescu, Oana Karampelas, Adina Magdalena Musuc, George Mihai Nițulescu, Emma Adriana Ozon, Georgiana Nițulescu, Cerasela Elena Gîrd, Catalina Fița, Dumitru Lupuliasa
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Processes
Subjects:
rutoside
β-cyclodextrin
hydroxypropyl-β-cyclodextrin
inclusion complexes
antioxidant activity
Online Access:https://www.mdpi.com/2227-9717/9/1/26

Internet

https://www.mdpi.com/2227-9717/9/1/26

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