The m6A RNA Demethylase ALKBH5 Promotes Radioresistance and Invasion Capability of Glioma Stem Cells

The m6A RNA Demethylase ALKBH5 Promotes Radioresistance and Invasion Capability of Glioma Stem Cells

Recurrence of GBM is thought to be due to GBMSCs, which are particularly chemo-radioresistant and characterized by a high capacity to invade normal brain. Evidence is emerging that modulation of m6A RNA methylation plays an important role in tumor progression. However, the impact of this mRNA modifi...

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Bibliographic Details
Main Authors: Aline Kowalski-Chauvel, Marie Géraldine Lacore, Florent Arnauduc, Caroline Delmas, Christine Toulas, Elizabeth Cohen-Jonathan-Moyal, Catherine Seva
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Cancers
Subjects:
glioblastomas
radio-resistance
signaling
ALKBH5
cancer stem cells
Online Access:https://www.mdpi.com/2072-6694/13/1/40

Internet

https://www.mdpi.com/2072-6694/13/1/40

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