Contribution of Somatic and Dendritic SK Channels in the Firing Rate of Deep Cerebellar Nuclei: Implication in Cerebellar Ataxia

Introduction: Loss of inhibitory output from Purkinje cells leads to hyperexcitability of the Deep Cerebellar Nuclei (DCN), which results in cerebellar ataxia. Also, inhibition of small-conductancecalcium-activated potassium (SK) channel increases firing rate  f DCN, which could cause cerebellar ata...

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Bibliographic Details
Main Authors: Samira Abbasi, Ataollah Abbasi, Yashar Sarbaz, Parviz Shahabi
Format: Article
Language:English
Published: Iran University of Medical Sciences 2016-01-01
Series:Basic and Clinical Neuroscience
Subjects:
Online Access:http://bcn.iums.ac.ir/browse.php?a_code=A-10-188-1&slc_lang=en&sid=1