Bioavailability of Orally Delivered Alpha- tocopherol by Poly(Lactic-Co-Glycolic) Acid (PLGA) Nanoparticles and Chitosan Covered PLGA Nanoparticles in F344 Rats

t is hypothesized that the bioavailability of αT (alpha- tocopherol), an antioxidant, can be improved when delivered by poly(lactic-co-glycolic) acid (PLGA) nanopar‐ ticles (NPs) and chitosan covered PLGA nanoparticles (PLGA-Chi NPs), and that the mucoadhesive properties of chitosan may enhance abso...

Full description

Bibliographic Details
Main Authors: Lacey C. Simon, Rhett W. Stout, Cristina Sabliov
Format: Article
Language:English
Published: SAGE Publishing 2016-04-01
Series:Nanobiomedicine
Subjects:
Online Access:http://www.intechopen.com/journals/nanobiomedicine/bioavailability-of-orally-delivered-alpha-tocopherol-by-poly-lactic-co-glycolic-acid-plga-nanopartic