Maternal expression relaxes constraint on innovation of the anterior determinant, bicoid.

The origin of evolutionary novelty is believed to involve both positive selection and relaxed developmental constraint. In flies, the redesign of anterior patterning during embryogenesis is a major developmental innovation and the rapidly evolving Hox gene, bicoid (bcd), plays a critical role. We re...

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Bibliographic Details
Main Authors: Michael S Barker, Jeffery P Demuth, Michael J Wade
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2005-11-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC1283158?pdf=render