Association Between Single Nucleotide Polymorphisms in PPARA and EPAS1 Genes and High-Altitude Appetite Loss in Chinese Young Men

Association Between Single Nucleotide Polymorphisms in PPARA and EPAS1 Genes and High-Altitude Appetite Loss in Chinese Young Men

Appetite loss is a common symptom that occurs in high altitude (HA) for lowlanders. Previous studies indicated that hypoxia is the initiating vital factor of HA appetite loss. PPARA, EPAS1, EGLN1, HIF1A, HIF1AN, and NFE2L2 play important roles in hypoxic responses. We aimed to explore the associatio...

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Bibliographic Details
Main Authors: Wenxu Pan, Chuan Liu, Jihang Zhang, Xubin Gao, Shiyong Yu, Hu Tan, Jie Yu, Dehui Qian, Jiabei Li, Shizhu Bian, Jie Yang, Chen Zhang, Lan Huang, Jun Jin
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Physiology
Subjects:
high altitude
appetite loss
hypoxia
PPARA
EPAS1
single nucleotide polymorphism
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2019.00059/full

Internet

https://www.frontiersin.org/article/10.3389/fphys.2019.00059/full

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