Absence of intestinal PPARγ aggravates acute infectious colitis in mice through a lipocalin-2-dependent pathway.

Absence of intestinal PPARγ aggravates acute infectious colitis in mice through a lipocalin-2-dependent pathway.

To be able to colonize its host, invading Salmonella enterica serovar Typhimurium must disrupt and severely affect host-microbiome homeostasis. Here we report that S. Typhimurium induces acute infectious colitis by inhibiting peroxisome proliferator-activated receptor gamma (PPARγ) expression in int...

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Bibliographic Details
Main Authors: Parag Kundu, Teo Wei Ling, Agata Korecka, Yinghui Li, Rossana D'Arienzo, Ralph M Bunte, Thorsten Berger, Velmurugesan Arulampalam, Pierre Chambon, Tak Wah Mak, Walter Wahli, Sven Pettersson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24465207/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24465207/?tool=EBI

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