Keratinocytes Isolated From Individual Cleft Lip/Palate Patients Display Variations in Their Differentiation Potential in vitro

Keratinocytes Isolated From Individual Cleft Lip/Palate Patients Display Variations in Their Differentiation Potential in vitro

To gain more understanding of the complex molecular processes underlying cleft lip/palate (CLP), we established a unique human cell bank, consisting of keratinocytes and corresponding fibroblasts from individual CLP patients as a new study tool. After their careful characterization, we used such pat...

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Bibliographic Details
Main Authors: Martin Degen, Astrid Wiederkehr, Giorgio C. La Scala, Christina Carmann, Isabelle Schnyder, Christos Katsaros
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Physiology
Subjects:
cleft lip/palate
keratinocytes
differentiation
IRF6
van der Woude Syndrome
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2018.01703/full

Internet

https://www.frontiersin.org/article/10.3389/fphys.2018.01703/full

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