Topological and kinetic determinants of the modal matrices of dynamic models of metabolism.

Large-scale kinetic models of metabolism are becoming increasingly comprehensive and accurate. A key challenge is to understand the biochemical basis of the dynamic properties of these models. Linear analysis methods are well-established as useful tools for characterizing the dynamic response of met...

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Bibliographic Details
Main Authors: Bin Du, Daniel C Zielinski, Bernhard O Palsson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5739448?pdf=render