Circulating TNF-alpha and IL-6 concentrations and TNF-alpha -308 G>A polymorphism in children with premature adrenarche

Circulating TNF-alpha and IL-6 concentrations and TNF-alpha -308 G>A polymorphism in children with premature adrenarche

Premature adrenarche (PA), the early rise in adrenal androgen production leading to prepubertal signs of androgen action, has been connected with adverse metabolic features. The metabolic syndrome is characterized by low grade inflammation which in turn is associated with increases in circulating pr...

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Bibliographic Details
Main Authors: Pauliina eUtriainen, Jarmo eJääskeläinen, Oskari eGröhn, Johanna eKuusisto, Kari ePulkki, Raimo eVoutilainen
Format: Article
Language:English
Published: Frontiers Media S.A. 2010-11-01
Series:Frontiers in Endocrinology
Subjects:
Adipose Tissue
Birth Weight
Interleukin 6
Body Mass Index
gene polymorphism
premature adrenarche
Online Access:http://journal.frontiersin.org/Journal/10.3389/fendo.2010.00006/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fendo.2010.00006/full

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