Functional Network Profiles in ARSACS Disclosed by Aptamer-Based Proteomic Technology

Functional Network Profiles in ARSACS Disclosed by Aptamer-Based Proteomic Technology

Although the genetic basis of autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS) has been uncovered, our poor understanding of disease mechanisms requires new light on functional pathways and modifying factors to improve early diagnostic strategies and offer alternative treatment opt...

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Bibliographic Details
Main Authors: Federica Morani, Stefano Doccini, Giovanna Chiorino, Fabiana Fattori, Daniele Galatolo, Elisa Sciarrillo, Federica Gemignani, Stephan Züchner, Enrico Silvio Bertini, Filippo Maria Santorelli
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Neurology
Subjects:
ARSACS
SomaLogic technology
sacsin
proteomic analysis
synaptogenesis
neuroinflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2020.603774/full

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https://www.frontiersin.org/articles/10.3389/fneur.2020.603774/full

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