Subcellular localization of iron and heme metabolism related proteins at early stages of erythrophagocytosis.

Subcellular localization of iron and heme metabolism related proteins at early stages of erythrophagocytosis.

BACKGROUND: Senescent red blood cells (RBC) are recognized, phagocytosed and cleared by tissue macrophages. During this erythrophagocytosis (EP), RBC are engulfed and processed in special compartments called erythrophagosomes. We previously described that following EP, heme is rapidly degraded throu...

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Bibliographic Details
Main Authors: Constance Delaby, Christiane Rondeau, Cécile Pouzet, Alexandra Willemetz, Nathalie Pilard, Michel Desjardins, François Canonne-Hergaux
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3408460?pdf=render

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http://europepmc.org/articles/PMC3408460?pdf=render

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