Combinatory transplantation of mesenchymal stem cells with flavonoid small molecule in acellular nerve graft promotes sciatic nerve regeneration

Previous animal studies have demonstrated that the flavonoid small-molecule TrkB agonist, 7, 8-dihydroxyflavone (DHF), promotes axon regeneration in transected peripheral nerves. In the present study, we investigated the combined effects of 7, 8-DHF treatment and bone marrow-derived stem/stromal cel...

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Bibliographic Details
Main Authors: Wen-yuan Li, Hua Jia, Zhen-Dong Wang, Feng-guo Zhai, Guang-da Sun, Duo Ma, Gui-Bo Liu, Chun-Mei Li, Ying Wang
Format: Article
Language:English
Published: SAGE Publishing 2020-12-01
Series:Journal of Tissue Engineering
Online Access:https://doi.org/10.1177/2041731420980136