Sublingual Bacterial Vaccination Reduces Recurrent Infections in Patients With Autoimmune Diseases Under Immunosuppressant Treatment

Sublingual Bacterial Vaccination Reduces Recurrent Infections in Patients With Autoimmune Diseases Under Immunosuppressant Treatment

IntroductionConventional or biologic disease-modifying anti-rheumatic drugs (DMARDs) are the mainstay of treatment for systemic autoimmune disease (SAD). Infectious complications are a major concern in their use.ObjectiveTo evaluate the clinical benefit of sublingual mucosal polybacterial vaccines (...

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Bibliographic Details
Main Authors: Silvia Sánchez-Ramón, Lidia Fernández-Paredes, Paula Saz-Leal, Carmen M. Diez-Rivero, Juliana Ochoa-Grullón, Concepción Morado, Pilar Macarrón, Cristina Martínez, Virginia Villaverde, Antonia Rodríguez de la Peña, Laura Conejero, Keyla Hernández-Llano, Gustavo Cordero, Miguel Fernández-Arquero, Benjamin Fernández- Gutierrez, Gloria Candelas
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Immunology
Subjects:
mucosal bacterial vaccines
recurrent infections
MV140
MV130
systemic autoimmune disease
biological therapies
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.675735/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.675735/full

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