A Chiron approach towards the stereoselective synthesis of polyfluorinated carbohydrates

Polyfluorinated hexopyranoses display unique physical, chemical and biological properties, however their stereoselective synthesis is highly challenging. Here, the authors report a synthetic approach based on the chemical manipulation of inexpensive levoglucosan to obtain heavily fluorinated monosac...

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Bibliographic Details
Main Authors: Vincent Denavit, Danny Lainé, Jacob St-Gelais, Paul A. Johnson, Denis Giguère
Format: Article
Language:English
Published: Nature Publishing Group 2018-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-06901-y