Platelet Derived Growth Factor-AA Correlates With Muscle Function Tests and Quantitative Muscle Magnetic Resonance in Dystrophinopathies

Platelet Derived Growth Factor-AA Correlates With Muscle Function Tests and Quantitative Muscle Magnetic Resonance in Dystrophinopathies

Introduction: Duchenne (DMD) and Becker (BMD) muscular dystrophy are X-linked muscular disorders produced by mutations in the DMD gene which encodes the protein dystrophin. Both diseases are characterized by progressive involvement of skeletal, cardiac, and respiratory muscles. As new treatment stra...

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Main Authors: Alicia Alonso-Jiménez, Esther Fernández-Simón, Daniel Natera-de Benito, Carlos Ortez, Carme García, Elena Montiel, Izaskun Belmonte, Irene Pedrosa, Sonia Segovia, Patricia Piñol-Jurado, Ana Carrasco-Rozas, Xavier Suárez-Calvet, Cecilia Jimenez-Mallebrera, Andrés Nascimento, Jaume Llauger, Claudia Nuñez-Peralta, Paula Montesinos, Jorge Alonso-Pérez, Eduard Gallardo, Isabel Illa, Jordi Díaz-Manera
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Neurology
Subjects:
PDGF
MRI
biomarker
Duchenne
Becker
dystrophinopathy
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2021.659922/full

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https://www.frontiersin.org/articles/10.3389/fneur.2021.659922/full

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