Association of SIX1/SIX6 locus polymorphisms with regional circumpapillary retinal nerve fibre layer thickness: The Nagahama study

Abstract SIX1 and SIX6 are glaucoma susceptibility genes. Previous reports indicate that the single nucleotide polymorphism (SNP) rs33912345 in SIX6 is associated with inferior circumpapillary retinal nerve fibre layer (cpRNFL) thickness (cpRNFLT). Although the region of visual field defect in glauc...

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Bibliographic Details
Main Authors: Munemitsu Yoshikawa, Kenji Yamashiro, Hideo Nakanishi, Manabu Miyata, Masahiro Miyake, Yoshikatsu Hosoda, Yasuharu Tabara, Fumihiko Matsuda, Nagahisa Yoshimura, the Nagahama Study Group
Format: Article
Language:English
Published: Nature Publishing Group 2017-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-02299-7