Transcript diversification in the nervous system: A to I RNA-editing in CNS function and disease development

RNA editing by adenosine deaminases that act on RNA converts adenosines to inosines in coding and non-coding regions of mRNAs. Inosines are interpreted as guanosines and hence, this type of editing can change codons, alter splice patterns, or influence the fate of an RNA. A to I editing is most abun...

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Bibliographic Details
Main Authors: Aamira eTariq, Michael F Jantsch
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-07-01
Series:Frontiers in Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnins.2012.00099/full