CLIC, a tool for expanding biological pathways based on co-expression across thousands of datasets.

In recent years, there has been a huge rise in the number of publicly available transcriptional profiling datasets. These massive compendia comprise billions of measurements and provide a special opportunity to predict the function of unstudied genes based on co-expression to well-studied pathways....

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Bibliographic Details
Main Authors: Yang Li, Alexis A Jourdain, Sarah E Calvo, Jun S Liu, Vamsi K Mootha
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-07-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC5546725?pdf=render