AiiM Lactonase Strongly Reduces Quorum Sensing Controlled Virulence Factors in Clinical Strains of Pseudomonas aeruginosa Isolated From Burned Patients

AiiM Lactonase Strongly Reduces Quorum Sensing Controlled Virulence Factors in Clinical Strains of Pseudomonas aeruginosa Isolated From Burned Patients

Pseudomonas aeruginosa is an opportunistic bacterium associated with healthcare infections in intensive care units (ICUs), ventilator-associated pneumonia (VAP), surgical site infections, and burns. This bacterium causes 75% of death in burned patients, since it can develop a persistent biofilm asso...

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Bibliographic Details
Main Authors: Luis Esaú López-Jácome, Georgina Garza-Ramos, Melissa Hernández-Durán, Rafael Franco-Cendejas, Daniel Loarca, Daniel Romero-Martínez, Phuong Thi Dong Nguyen, Toshinari Maeda, Bertha González-Pedrajo, Miguel Díaz-Guerrero, Jorge Luis Sánchez-Reyes, Dánae Díaz-Ramírez, Rodolfo García-Contreras
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Microbiology
Subjects:
AiiM lactonase
virulence factors
Pseudomonas aeruginosa
quorum quenching
burned patients
anti-virulence therapy
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.02657/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2019.02657/full

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