Aberrantly Expressed Galectin-9 Is Involved in the Immunopathogenesis of Anti-MDA5-Positive Dermatomyositis-Associated Interstitial Lung Disease

Aberrantly Expressed Galectin-9 Is Involved in the Immunopathogenesis of Anti-MDA5-Positive Dermatomyositis-Associated Interstitial Lung Disease

BackgroundDermatomyositis (DM) associated rapidly progressive interstitial lung disease (RP-ILD) has high mortality rate and poor prognosis. Galectin-9 (Gal-9) plays multiple functions in immune regulation. We investigated Gal-9 expression in DM patients and its association with DM-ILD.MethodsA tota...

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Bibliographic Details
Main Authors: Lin Liang, Ya-Mei Zhang, Ya-Wen Shen, Ai-Ping Song, Wen-Li Li, Li-Fang Ye, Xin Lu, Guo-Chun Wang, Qing-Lin Peng
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
galectin-9
interstitial lung disease
melanoma differentiation-associated gene 5
biomarker
dermatomyositis
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.628128/full

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https://www.frontiersin.org/articles/10.3389/fcell.2021.628128/full

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