Pressure load: the main factor for altered gene expression in right ventricular hypertrophy in chronic hypoxic rats.

The present study investigated whether changes in gene expression in the right ventricle following pulmonary hypertension can be attributed to hypoxia or pressure loading.To distinguish hypoxia from pressure-induced alterations, a group of rats underwent banding of the pulmonary trunk (PTB), sham op...

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Bibliographic Details
Main Authors: Jonas D Baandrup, Lars H Markvardsen, Christian D Peters, Uffe K Schou, Jens L Jensen, Nils E Magnusson, Torben F Ørntoft, Mogens Kruhøffer, Ulf Simonsen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3016335?pdf=render