Identification of novel radiation-induced p53-dependent transcripts extensively regulated during mouse brain development

Identification of novel radiation-induced p53-dependent transcripts extensively regulated during mouse brain development

Ionizing radiation is a potent activator of the tumor suppressor gene p53, which itself regulates the transcription of genes involved in canonical pathways such as the cell cycle, DNA repair and apoptosis as well as other biological processes like metabolism, autophagy, differentiation and developme...

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Bibliographic Details
Main Authors: Roel Quintens, Tine Verreet, Ann Janssen, Mieke Neefs, Liselotte Leysen, Arlette Michaux, Mieke Verslegers, Nada Samari, Giuseppe Pani, Joris Verheyde, Sarah Baatout, Mohammed A. Benotmane
Format: Article
Language:English
Published: The Company of Biologists 2015-02-01
Series:Biology Open
Subjects:
Alternative splicing
Development
Embryonic brain
Ionizing radiation
Neuronal differentiation
p53 targets
Online Access:http://bio.biologists.org/content/4/3/331

Internet

http://bio.biologists.org/content/4/3/331

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