Synthesis and in Silico Evaluation of Novel Compounds for PET-Based Investigations of the Norepinephrine Transporter

Synthesis and in Silico Evaluation of Novel Compounds for PET-Based Investigations of the Norepinephrine Transporter

Since the norepinephrine transporter (NET) is involved in a variety of diseases, the investigation of underlying dysregulation-mechanisms of the norepinephrine (NE) system is of major interest. Based on the previously described highly potent and selective NET ligand 1-(3-(methylamino)-1-phenylpropyl...

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Bibliographic Details
Main Authors: Catharina Neudorfer, Amir Seddik, Karem Shanab, Andreas Jurik, Christina Rami-Mark, Wolfgang Holzer, Gerhard Ecker, Markus Mitterhauser, Wolfgang Wadsak, Helmut Spreitzer
Format: Article
Language:English
Published: MDPI AG 2015-01-01
Series:Molecules
Subjects:
NET
ADHD
cocaine dependence
BAT
PET
FAPPI
Online Access:http://www.mdpi.com/1420-3049/20/1/1712

Internet

http://www.mdpi.com/1420-3049/20/1/1712

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