Mitochondrial dysfunction in Pten haplo-insufficient mice with social deficits and repetitive behavior: interplay between Pten and p53.

Mitochondrial dysfunction in Pten haplo-insufficient mice with social deficits and repetitive behavior: interplay between Pten and p53.

Etiology of aberrant social behavior consistently points to a strong polygenetic component involved in fundamental developmental pathways, with the potential of being enhanced by defects in bioenergetics. To this end, the occurrence of social deficits and mitochondrial outcomes were evaluated in con...

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Bibliographic Details
Main Authors: Eleonora Napoli, Catherine Ross-Inta, Sarah Wong, Connie Hung, Yasuko Fujisawa, Danielle Sakaguchi, James Angelastro, Alicja Omanska-Klusek, Robert Schoenfeld, Cecilia Giulivi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3416855?pdf=render

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http://europepmc.org/articles/PMC3416855?pdf=render

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